InVi SPIM Lattice Pro

The InVi SPIM Lattice Pro provides the highest level of flexibility for illuminating samples using a proprietary Advanced Illumination Module (AIM). It expands the capabilities of the InVi SPIM: while maintaining the ease-of-use and stability of the system, it adds tailorable, interactive adaptability of the beam shape to suit the highly specific requirements of your sample. You choose what gives you the best results for your 3D high resolution imaging experiment – large field of view, high speed or optimal spatial resolution.

Illumination and Detection

The InVi SPIM Lattice Pro offers a variety of illumination patterns, ranging from the classical static Gaussian light-sheet or a scanned Gaussian beam to sophisticated illumination schemes like Bessel beams, Airy beams or optical lattices.

The user can select from a broad choice of beam shapes to improve the microscope’s resolution and reduce photo-damage in delicate samples. A Special Optics 28.6x 0.7 NA water immersion objective lens projects the light-sheet on the sample. A high numerical aperture Nikon CFI Apo 25x W 1.1 NA water immersion objective lens images the signal onto one or two Hamamatsu sCMOS cameras. An additional magnification changer provides 31.3x and 62.5x total magnification to allow you to optimize field of view and pixel size to your experimental needs.


Live Sample Applications

Browse a selection of applications data from our customers below. Researchers are using the InVi SPIM Lattice Pro in a variety of ways including studies in embryogenesis and developmental biology, organoids, cell cultures, neurobiology and neurodevelopment, plants, and more.

All-in-One LuxBundle Software


Intuitive design

Bruker's LuxBundle software saves time and enhances productivity by providing:

  • All-in-one, easy-to-use interface for acquisition, viewing, and post-processing
  • Fully scriptable microscope control and post-processing via open interface (e.g., Python or any other language) ready for custom "smart" microscopy
  • High reproducibility of experiments: all parameters are saved in the metadata and configurations can be saved for future experiments
  • Data formats (.tiff, .hdf5, .ims) compatible with common image processing software: Imaris, Aivia, BigDataViewer, Arivis, Fiji, Python, Matlab, Napari


Impressive Image Post Processor

MuVi SPIM records a sample from different angles/views and generates images composed of multiple tiles. The LuxBundle software ensures high-quality, 360° crisp images of the sample that compensate for absorption and scattering. Features include:

  • Multi-color alignment
  • Tile stitching of hundreds of tiles for large samples
  • Multi-view image fusion and deconvolution


  • View LuxBundle Webinar


3D Data Viewer

LuxBundle's integrated 3D data viewer allows researchers to inspect the entire dataset directly after acquisition. This gives users control over their data with key capabilities, including:

  • The ability to turn tile stitching on or off
  • Both raw and post-processed images
  • Fast viewing of multi-terabyte data sets
  • Flexible options to draw and annotate regions and landmarks